Pathobiochemistry means biochemistry of disease In the curriculum of medical studies it may serve as a useful and highly enjoyable “bridge” between the basic science of the first years and the clinical training later Practical limitations dictate that from a vast area of human pathology a careful selection of topics must be made The eleven chapters of this book deal with the basics of acid base balance disorders inflammation reactive oxygen species and antioxidant defense non enzymatic glycations atherosclerosis metabolic syndrome ischemia reperfusion of the heart protein misfolding disorders ageing and consequences of alcohol abuse The selection covers some pathogenetic processes behind several important medical problems of the present Further it more or less implicitly points to the inner causes of diseases The inner maintenance of body structural and chemical integrity is costly and has its limits that regularly get exceeded which is the ultimate reason for ageing and contributes to many often also age related civilization diseases
